← All questionsGS3 · 2022 · Internal Security ·Vaccine Science and India's COVID-19 Vaccines
QUESTION 16
GS3
15 marks

What is the basic principle behind vaccine development? How do vaccines work? What approaches were adopted by the Indian vaccine manufacturers to produce COVID-19 vaccines?

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11 min
250 words

What the examiner wants

Explain the principle behind vaccines, how they work, and the approaches used by Indian makers of COVID-19 vaccines.

ExplainMake clear how and why it happens: causes, process, and an example for each point.

Demand-wise check

  1. 1Principle: train the immune system with an antigen without causing disease≈65 words
  2. 2How they work: antibodies and memory B and T cells≈65 words
  3. 3Indian approaches: Covishield (viral vector), Covaxin (inactivated), ZyCoV-D (DNA), Corbevax (protein subunit), GEMCOVAC (mRNA)≈65 words

Open in about 30 words and close in about 30.

Answer plan

PrincipleMechanismIndian platformsConclusion

Where marks usually go

  • Missing one of the three parts
  • Not naming platforms

Draw this

  • Table: vaccine → maker → platform

Value addition

  • FactZyCoV-D was the world's first DNA vaccine approved for human use (2021).Zydus / DCGI
  • FactCovaxin was developed by Bharat Biotech with ICMR-NIV.ICMR

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